Lubrizol, a global leader in advanced specialty ingredients, has announced a significant milestone in its journey towards sustainability: the elimination of perfluoroalkyl and polyfluoroalkyl substances (PFAS), including trifluoroacetic acid (TFA), from its peptide synthesis process. As of this June, Lubrizol has added three peptides to its product portfolio, synthesized without PFAS. This advancement reflects Lubrizol's commitment to green chemistry and environmental responsibility, and adds to the range of naturally derived peptides that the company has launched since 2020.
Although the use of PFAS in cosmetic ingredients is limited and not usually present in final formulations, Lubrizol has decided to take a proactive step by eliminating these substances from peptide synthesis processes, due to global environmental concerns and tightening regulations.
The three new PFAS-free peptides (Uplevity™ peptide, Uplevity™ e-Lift peptide and Leuphasyl® peptide) represent Lubrizol's new generation of peptide design. These ingredients are produced by solid phase peptide synthesis (SPPS), a Nobel Prize-winning method that typically requires reagents such as TFA, a PFAS. Although TFA is not incorporated into final cosmetic products and is currently outside the scope of some regulations in the USA, evolving restrictions in both the USA and the EU reinforce the importance of Lubrizol's visionary approach.
Lubrizol has prioritized a scientific, performance-validated approach to ensure that its PFAS-free peptides meet the highest standards of quality and functionality. "We recognize that sustainability is not just about being first, but about doing it right," says Elena Cañadas. "Our PFAS-free peptides are the result of meticulous formulation work, regulatory forecasting and a deep respect for the planet."