Vytrus Biotech, a company specialised in plant biotechnology-derived active ingredients for the cosmetics industry, has presented its latest research on plant exosomes for skin and hair care based on plant biotechnology at in-cosmetics Global in Paris and brings the concept of Exosomic Peptides to the cosmetics industry.
Exosomes, also known as ectosomes or small extracellular vesicles (EVPs), are bounded by a lipid membrane and are naturally secreted by cells. Exosomes contain DNA, RNA, lipids, proteins, cytokines, transcription factor receptors, heat shock proteins, enzymes, antioxidants and other bioactive compounds.
Vytrus conceives exosomes as "natural biological communicators" that carry packets of relevant biological information. Within the cosmetic industry, exosomes provide different beneficial properties: anti-inflammatory and anti-aging effect, immunomodulatory properties, healing, hydration, synthesis of extracellular matrix proteins (collagen, elastin, etc.), skin protection, microbiota modulation, regeneration and skin homeostasis, among others.
Lately, there has been an explosion in the cosmetic industry around synthetic/biomimetic exosomes (synthetically produced vesicles with similar functions to exosomes but structurally very different). In parallel, Vytrus has just unveiled structurally intact natural plant exosomes with all their rich content, transferred from the plant to the human body through cosmetics. These plant exosomes are structurally similar to those of mammals, so they can penetrate and transmit molecular information to our human cells very efficiently, enabling Cross-Realm Communication in cosmetics.
The biotech company has demonstrated the production and characterisation of real plant exosomes from plant cell cultures using its biotech platforms. Its plant cell cultures show a high concentration of exosomes compared to traditional plant sources, reaching levels of billions of exosomes/ml. Thanks to Vytrus' technology platforms, it is possible to customise and guide plant cells to produce different types of exosomes for skin and hair care.
The Curcuma longa cell cultures developed by Vytrus Biotech include a high concentration of exosomes at the billion level. These exosomes have very interesting applications in improving skin hydration and regeneration, as well as increasing hair density and delaying hair loss.
Vytrus has also developed cell cultures of Centella asiatica with a high concentration of exosomes in the billions. These natural exosomes have the potential to encapsulate and protect compounds of interest such as growth factors, proteins and peptides. These Centella exosomes are able to activate expression patterns of skin genes related to ageing, the skin barrier and hydration in keratinocytes (increased expression of type I collagen, inhibition of elastase, etc.) with potent regenerative and anti-wrinkle effects on the skin. A cocktail of properties leading to the reversal of cellular senescence.
In its aim to advance cutting-edge cosmetic science, Vytrus has also analysed what is contained in its plant exosomes. After in-depth research, the biotech company has found an astonishing diversity of plant peptides in the content of its natural plant exosomes, coined by Vytrus as Exosomic Peptides for the first time in cosmetics. This great diversity of different peptides identified in Vytrus exosomes provides a huge cocktail of natural plant peptides with anti-ageing, anti-inflammatory, anti-wrinkle and other activities.
These active principles based in exosomas of Vytrus are very effective in the skin and the hair and have a big potential of innovation in cosmetic thanks to a sustainable vegetal biotechnology that is changing the approach of the demand of the consumers in his routines of care of the skin and the hair. It discovers this last innovation contacting with the technical team of Vytrus Biotech.