Special Chemicals presents a plant-based PDRN proposal obtained through an advanced process aimed at maximizing purity, safety, and consistency in cosmetic applications. The range is characterized by being free of chemical solvents and free of animal origin.
The line includes five variants inspired by botanicals with sensory and cosmetic benefit positioning: Centella asiatica PDRN, Rosa damascena PDRN, Sea Grape PDRN, Black Garlic PDRN, and Poppy PDRN; designed to address needs such as comfort, hydration, elasticity, regeneration, and barrier reinforcement.
Regarding available evidence, results from in vitro and in vivo trials have been obtained, focusing on cosmetic mechanisms, with readings on biomarkers associated with hydration, elasticity, dermal structure, and skin comfort. Depending on the variant, improvements are observed in markers related to hyaluronic acid synthesis (HAS-2 and HAS-3), extracellular matrix and collagen (COL1A1), and enzymes linked to elasticity/structure (LOX), as well as modulation trends in markers associated with inflammatory response such as cytokines. Furthermore, comparisons have been made against the reference salmon-derived PDRN, with contrasted results to evaluate the relative performance of plant-based PDRN under equivalent testing conditionsWith this range, Special Chemicals reinforces its offering of plant-based solutions, alongside ceramides, for brands seeking alternatives to animal-derived PDRN, maintaining a positioning aligned with responsible formulation trends