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Tranexamic acid, niacinamide and professional personalization: this is how Germaine de Capuccini's Pigment Therapy evolves

Germaine de Capuccini presents a new generation of Pigment Therapy, a system in which advanced cosmetic science joins expert skin knowledge to address hyperpigmentation from a professional perspective

23 of October of 2026
Pigment Therapy Germaine de Capuccini

Skin pigmentation is a complex phenomenon involving different mechanisms, and its evolution can be conditioned by factors such as sun exposure, inflammatory processes, hormonal changes, or aging.

Therefore, addressing spots does not necessarily mean acting on a single mechanism or applying the same protocol to all skin types. Diagnosis, treatment intensity, skin tolerance, home continuity, and professional follow-up play a fundamental role.

Based on this vision, Germaine de Capuccini presents the new generation of Pigment Therapy, which evolves its formulas and expands customization possibilities, allowing for more precise modulation of treatment intensity and adapting the home routine to the needs of each skin.

From science to personalization: the professional decides how to approach each skin

If pigmentation responds to diverse mechanisms, the treatment does not have to be identical in all cases. One of the pillars of Pigment Therapy is to transfer scientific knowledge to the diagnosis and decision-making of the professional.

Based on an expert assessment, the professional can adapt the modality and intensity of the peeling, the frequency of sessions, the technique and technology used, support products, and the home routine according to the skin's condition, tolerance, and evolution. Follow-up allows reviewing this routine and adjusting it when necessary.

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Two levels of peeling to modulate intensity

Within Advanced Pigment Control, the professional in-cabin protocol of Pigment Therapy, the system incorporates two peeling options.

Correction Peel allows working from a progressive or maintenance routine, while the new Correction Peel Intense offers a more powerful alternative when the treatment objective and skin tolerance require it.

Correction Peel Intense combines different acids, including succinic acid, lactobionic acid, glycolic acid, and lactic acid, to intensify epidermal renewal and promote a more intense corrective action on spots. Its incorporation allows the professional to opt for a progressive or intensive intervention depending on each case.

Another new product is Advanced Dark Spot Mask, a professional facial mask with niacinamide and soothing active ingredients. Its texture has been reformulated to offer a creamier and more comfortable application, maintaining a prolonged action and a more natural finish at the end of the session. It does not need to be removed, facilitating the return to daily activity after the treatment.

Tranexamic acid, niacinamide, and vitamin C to prolong at-home treatment

In addressing pigmentation, the work does not end when leaving the cabin. The continuity between professional treatment and home care is part of the approach of Pigment Therapy.

The new Dark Spot Emulsion incorporates tranexamic acid, niacinamide, and a stable derivative of vitamin C, along with a soothing agent. Its formula acts on different mechanisms involved in hyperpigmentation and expands the professional's recommendation possibilities.

It can be used individually or combined with the Dark Spot Minimizing Concentrate, depending on the skin and the stage of treatment. The combination of both continues to be the complete regimen evaluated by the brand and the recommendation to achieve maximum synergy, while the new approach allows for a more flexible prescription according to the needs of each case.

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A system that acts on different stages of the pigmentation process

The cosmetic technology 4-PATH SYSTEM organizes the action of Pigment Therapy through four complementary pathways related to the formation and evolution of spots: exfoliation, synthesis, transfer, and protection.

Exfoliation promotes the elimination of hyperpigmented keratinocytes and prepares the skin for subsequent cosmetic treatment. The action on synthesis helps regulate the activity of tyrosinase, an enzyme involved in melanin production, while the action on transfer intervenes in the transport of melanin during the skin renewal process.

The fourth pathway focuses on protection, seeking to limit signals that stimulate pigmentation and complement the other actions of the system.

Photoprotection as part of pigmentation control

The system also incorporates Daily Hi-Defense SPF50 Mineral, a 100% mineral broad-spectrum photoprotector formulated with zinc oxide and titanium dioxide. With a light texture and dry finish, it is indicated for all skin types, especially sensitive or sensitized skin, both within the professional protocol and in daily care.

Photoprotection plays an essential role in maintenance, as pigmentation can reactivate over time. Pigment Therapy thus contemplates not only the correction of existing spots, but also their subsequent control.

Professional technology and medical-aesthetic complementarity

Personalization also extends to the choice of technology. Advanced Pigment Control is designed to integrate with Germaine de Capuccini's professional devices, including Expert Jet, and can also be combined with other compatible technologies, following the recommendations established for each equipment and product.

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In addition, Pigment Therapy can be approached from two perspectives: as a professional, non-invasive and customizable cosmetic solution, or as complementary care during or after certain medical-aesthetic procedures, with the aim of helping to enhance, maintain and prolong their results, always under professional criteria.

Clinical results after four professional sessions

The new generation of Pigment Therapy has results from dermatological clinical evaluation and instrumental measurements.

After four in-cabin sessions and one month of home treatment in 21 volunteers, a mean reduction of 28.5% in spot intensity was observed through dermatological clinical evaluation and a 42.9% improvement in tone contrast through ITA instrumental measurement.

Measurements made with VisioFace Lite also recorded a 20.5% reduction in the percentage of visible spots and a 23% reduction in the percentage of spots measured under UV light.

Before and after Pigment Therapy treatment

The brand frames these data under the concept of “visible results, responsible promise”: the results correspond to the specific conditions of the study and are not presented as a universal answer, since the evolution of pigmentation depends on the characteristics of each skin and multiple factors.

Science, expert knowledge and continuity

With this new generation, Germaine de Capuccini starts from a clear premise: the complexity of pigmentation requires combining science, expert knowledge, and personalization.

Because when faced with a phenomenon as complex as pigmentary alterations, innovation does not consist solely of incorporating new active ingredients, but also in knowing how, when, and with what intensity to use them.