Mediderma, the professional aesthetic medicine division of Grupo Sesderma, presents EXOSES Global Regen, a new high-end line inspired by regenerative medicine and developed to transfer its advances to home care. Available exclusively in medical clinics, it is designed to preserve skin quality and keep it healthier, more balanced, and resilient as the years go by.
Its formula combines probiotic-derived exosomes and PDRN with amino acids, succinic acid, and other selected active ingredients to comprehensively improve skin quality. The line consists of two complementary products: EXOSES Global Regen Rejuvenating serum glow effect and EXOSES Global Regen Rejuvenating cream.
Exosomes and PDRN: the science behind the formula
The main protagonists of EXOSES Global Regen are exosomes and PDRN, two active ingredients that act synergistically on different aspects related to skin quality.
Exosomes are small extracellular vesicles that act as messengers between cells. They are capable of transporting information packages related to tissue balance and functionality. Those used by Mediderma are of probiotic origin obtained from Lactobacillus brevis. Their action contributes to strengthening the barrier function, helping the skin to remain protected, hydrated, and more resilient against external aggressions.
For its part, salmon PDRN (polydeoxyribonucleotide) is made up of small fragments of DNA and is linked to skin repair and renewal processes and the maintenance of firmer and more elastic skin.
This combination is joined by active ingredients such as niacinamide, centella asiatica, ceramides, hyaluronic acid, and panthenol, which help maintain hydration and the balance of the skin barrier; growth factors, amino acids, and succinic acid, related to renewal and collagen synthesis; and antioxidants such as vitamin C, glutathione, and ginkgo biloba, which contribute to protecting the skin against oxidative stress and enhancing its luminosity.
In this way, EXOSES Global Regen addresses three dimensions of skin quality: it strengthens skin health and resilience, promotes a more rejuvenated appearance, and enhances its vitality and luminosity.
More luminous, hydrated, and even skin in 28 days
The user experience supports the benefits of this combination. After jointly applying the serum and cream twice a day for four weeks, 100% of volunteers perceived their skin as more luminous and hydrated, 94% noticed it was more even, and 91% observed an overall improvement in their skin.
Additionally, 91% appreciated an improvement in texture and 76% perceived their skin as more rejuvenated.
The data comes from a subjective study conducted with 33 volunteers aged between 30 and 65 over 28 days.
Two formulas that work in synergy
EXOSES Global Regen Rejuvenating Serum glow effect
A light-textured serum that strengthens the barrier function, improves hydration, and reveals more revitalized and even skin. Its formula combines exosomes and PDRN with active ingredients such as niacinamide, centella asiatica, ceramides, hyaluronic acid, vegetable oils, vitamin C, and ginkgo biloba. Additionally, it incorporates luminous pigments that provide an immediate glow effect, enhancing the skin's natural luminosity.
EXOSES Global Regen Rejuvenating Cream
The routine is completed with a light-textured cream formulated to nourish, strengthen the barrier function, and improve skin elasticity, promoting healthier-looking, redensified, and rejuvenated skin. Along with exosomes and PDRN, it incorporates growth factors, amino acids, succinic acid, shea butter, vegetable oils, panthenol, and glutathione.